SCHEMBL30406580

SCHEMBL30406580

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)NCCCC[C@H](NC(=O)CCCNC(=O)/C=C/C(=O)OC)C(=O)NCCCC(=O)NCC(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.47
▸ CAPN1 P07384 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.32
▸ LPAR3 Q9UBY5 2/20 0.31
▸ TLR2 O60603 4/20 0.31
▸ TSHR P16473 1/20 0.31
▸ CA1 P00915 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ NMT2 O60551 1/20 0.30
▸ NMT1 P30419 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30407101 0.94 GLP1R (0.49) GLP1RCAPN1TDP1LPAR3TLR2
SCHEMBL30407637 0.90 GLP1R (0.53) GLP1RLPAR3TLR2TSHRNMT2
SCHEMBL25551866 0.89 GLP1R (0.52) GLP1RLPAR3TSHRNMT2NMT1
SCHEMBL29467628 0.84 GLP1R (0.47) GLP1RCAPN1TDP1LPAR3TLR2
SCHEMBL30407445 0.83 GLP1R (0.46) GLP1RCAPN1TDP1CA1CA2
SCHEMBL29467696 0.82 GLP1R (0.46) GLP1RTLR2NMT2NMT1
SCHEMBL30407201 0.81 GLP1R (0.45) GLP1RCAPN1TDP1CA1CA2
SCHEMBL30410601 0.81 GLP1R (0.44) GLP1RCAPN1TDP1TLR2CA1
SCHEMBL30407248 0.80 GLP1R (0.44) GLP1RCAPN1TDP1CA1CA2
SCHEMBL30407264 0.80 GLP1R (0.43) GLP1RCAPN1TDP1TLR2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4426741-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE Hangzhou DAC Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
EP-4426729-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
WO-2023078021-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
WO-2023078273-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
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