SCHEMBL30407101

SCHEMBL30407101

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)NCCCCC(NC(=O)CCCNC(=O)C=CC(=O)O)C(=O)NCCCC(=O)NCC(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.49
▸ CAPN1 P07384 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.32
▸ LPAR3 Q9UBY5 2/20 0.31
▸ PSEN1 P49768 1/20 0.31
▸ PSEN2 P49810 1/20 0.31
▸ APH1B Q8WW43 1/20 0.31
▸ NCSTN Q92542 1/20 0.31
▸ APH1A Q96BI3 1/20 0.31
▸ PSENEN Q9NZ42 1/20 0.31
▸ TLR2 O60603 1/20 0.31
▸ NOD1 Q9Y239 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ SIRT2 Q8IXJ6 1/20 0.31
▸ SIRT5 Q9NXA8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30406580 0.94 GLP1R (0.47) GLP1RCAPN1TDP1LPAR3TLR2
SCHEMBL30407637 0.85 GLP1R (0.53) GLP1RLPAR3TLR2NOD1TSHR
SCHEMBL29467628 0.84 GLP1R (0.47) GLP1RCAPN1TDP1LPAR3TLR2
SCHEMBL25551866 0.84 GLP1R (0.52) GLP1RLPAR3NOD1TSHRSIRT2
SCHEMBL30407445 0.83 GLP1R (0.46) GLP1RCAPN1TDP1SIRT2SIRT5
SCHEMBL29467696 0.82 GLP1R (0.46) GLP1RTLR2
SCHEMBL30407201 0.81 GLP1R (0.45) GLP1RCAPN1TDP1
SCHEMBL30410601 0.81 GLP1R (0.44) GLP1RCAPN1TDP1TLR2
SCHEMBL30407248 0.80 GLP1R (0.44) GLP1RCAPN1TDP1PSEN1PSEN2
SCHEMBL30408018 0.80 GLP1R (0.43) GLP1RCAPN1TDP1TLR2SIRT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4426741-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE Hangzhou DAC Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
EP-4426729-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
WO-2023078021-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
WO-2023078273-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
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