SCHEMBL30407159

SCHEMBL30407159

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)NCCCC[C@H](NC(=O)CCCN1C(=O)C=CC1=O)C(=O)NCCCC(=O)NCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.43
▸ HPGD P15428 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ TP53 P04637 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ TSHR P16473 1/20 0.32
▸ AKT1 P31749 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ EGLN1 Q9GZT9 1/20 0.31
▸ KDM2A Q9Y2K7 1/20 0.31
▸ LTB4R Q15722 1/20 0.31
▸ ROCK2 O75116 2/20 0.31
▸ PRKACA P17612 1/20 0.31
▸ AKT3 Q9Y243 1/20 0.31
▸ TPSAB1 Q15661 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25686533 0.99 GLP1R (0.42) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL25682703 0.98 GLP1R (0.41) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL29467590 0.95 GLP1R (0.41) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL23451371 0.95 GLP1R (0.43) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL29467678 0.95 GLP1R (0.43) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL23451368 0.95 GLP1R (0.43) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL30408933 0.94 GLP1R (0.40) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL29467730 0.93 GLP1R (0.40) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL30407031 0.91 GLP1R (0.39) GLP1RHPGDHTTSMN1; SMN2
SCHEMBL25555849 0.90 GLP1R (0.37) GLP1RHPGDHTTSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4426741-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE Hangzhou DAC Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
EP-4426729-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
WO-2023078021-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
WO-2023078273-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
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