SCHEMBL23451368

SCHEMBL23451368

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)NCCCC[C@H](NC(=O)CCCN1C(=O)C=CC1=O)C(=O)NCCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.43
▸ HPGD P15428 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ TP53 P04637 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ ROCK2 O75116 2/20 0.32
▸ PRKACA P17612 1/20 0.32
▸ AKT3 Q9Y243 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ EGLN1 Q9GZT9 1/20 0.31
▸ KDM2A Q9Y2K7 1/20 0.31
▸ NAMPT P43490 1/20 0.31
▸ FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29467678 1.00 GLP1R (0.43) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL23451371 1.00 GLP1R (0.43) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL29467730 0.96 GLP1R (0.40) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL29467590 0.96 GLP1R (0.41) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL30408933 0.95 GLP1R (0.40) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL30407159 0.95 GLP1R (0.43) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL25686533 0.94 GLP1R (0.42) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL25682703 0.93 GLP1R (0.41) GLP1RHPGDHTTSMN1; SMN2TP53
SCHEMBL29467675 0.91 GLP1R (0.39) GLP1RHPGDHTTSMN1; SMN2ROCK2
SCHEMBL29467571 0.91 HPGD (0.45) GLP1RHPGDHTTSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2025-11-06 — — US disclosed
US-20210169896-A1 A CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES HANGZHOU DAC BIOTECH CO., LTD. (CN) 2021-06-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES FCGR2A, FCGR3B, FCGR1A GLP1R 2116/4885HPGD 3598/4885HTT 2413/4885
US-20210169896-A1 A CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES PBDC1, BRD2, CD79B GLP1R 4709/4885HPGD 1151/4885HTT 3654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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