Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.49 |
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30408074 | 1.00 | SIRT2 (0.49) | SIRT2SIRT1KLK7KLK5PSMB5 | |
| SCHEMBL30407457 | 0.98 | SIRT2 (0.50) | SIRT2SIRT1KLK7KLK5HDAC4 | |
| SCHEMBL30406566 | 0.95 | SIRT2 (0.48) | SIRT2SIRT1KLK7KLK5HDAC4 | |
| SCHEMBL30407623 | 0.94 | SIRT2 (0.46) | SIRT2SIRT1KLK7KLK5PSMB5 | |
| SCHEMBL30407331 | 0.91 | SIRT2 (0.49) | SIRT2SIRT1KLK7KLK5PSMB5 | |
| SCHEMBL29548828 | 0.88 | PSMB5 (0.53) | SIRT2SIRT1PSMB5 | |
| SCHEMBL29813489 | 0.87 | MAPT (0.56) | SIRT2SIRT1KLK7KLK5SIRT3 | |
| SCHEMBL23451323 | 0.87 | SIRT2 (0.52) | SIRT2SIRT1KLK7KLK5SIRT3 | |
| SCHEMBL23451322 | 0.87 | SIRT2 (0.52) | SIRT2SIRT1KLK7KLK5SIRT3 | |
| SCHEMBL29467658 | 0.87 | SIRT2 (0.52) | SIRT2SIRT1KLK7KLK5SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426741-A1 | BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE | Hangzhou DAC Biotech Co., Ltd. (CN) | 2024-09-11 | — | — | EP | disclosed |
| EP-4426729-A1 | SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE | Hangzhou Dac Biotech Co., Ltd. (CN) | 2024-09-11 | — | — | EP | disclosed |
| WO-2023078021-A1 | BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023078273-A1 | SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-05-11 | — | — | WO | disclosed |