Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 3/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29467688 | 0.90 | LMNA (0.49) | CTSBSYKCAPN1CAPN2CTSK | |
| SCHEMBL30408074 | 0.88 | SIRT2 (0.49) | PSMB5SIRT2SIRT1 | |
| SCHEMBL30407209 | 0.88 | SIRT2 (0.49) | PSMB5SIRT2SIRT1 | |
| SCHEMBL30407457 | 0.86 | SIRT2 (0.50) | SIRT2SIRT1 | |
| SCHEMBL29467624 | 0.85 | CAPN1 (0.51) | CTSBCAPN1CAPN2SIRT2BCHE | |
| SCHEMBL30638287 | 0.84 | LMNA (0.52) | PSMB5CTSBSYKCAPN1CAPN2 | |
| SCHEMBL19509744 | 0.84 | LMNA (0.52) | PSMB5CTSBSYKCAPN1CAPN2 | |
| SCHEMBL25132765 | 0.84 | SYK (0.49) | PSMB5CTSBSYKCAPN1CAPN2 | |
| SCHEMBL29467642 | 0.83 | LMNA (0.54) | CAPN1CAPN2LMNASMN1; SMN2SIRT2 | |
| SCHEMBL29336444 | 0.83 | LMNA (0.54) | CTSBCAPN1CAPN2CTSKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986463-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2022-04-27 | — | — | EP | disclosed |