SCHEMBL30407351

SCHEMBL30407351

NC(=O)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 15/20 0.63
▸ OPRM1 P35372 9/20 0.63
▸ OPRK1 P41145 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29630599 0.94 OPRD1 (0.63) OPRD1OPRM1OPRK1
SCHEMBL11578512 0.90 OPRD1 (0.66) OPRD1OPRM1OPRK1
SCHEMBL9052245 0.90 OPRD1 (0.70) OPRD1OPRM1OPRK1
SCHEMBL29354962 0.90 OPRD1 (0.70) OPRD1OPRM1OPRK1
SCHEMBL29679587 0.89 OPRD1 (0.59) OPRD1OPRM1OPRK1
SCHEMBL30123118 0.89 OPRD1 (0.56) OPRD1OPRM1OPRK1
SCHEMBL29839256 0.89 OPRD1 (0.56) OPRD1OPRM1OPRK1
SCHEMBL29630566 0.88 OPRD1 (0.55) OPRD1OPRM1OPRK1
SCHEMBL30545070 0.88 OPRD1 (0.72) OPRD1OPRM1OPRK1
SCHEMBL29350666 0.88 OPRD1 (0.72) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240391951-A1 NOVEL METHODS FOR PRODUCING PEPTIDE THIOESTER AND PEPTIDE GLYTECH INC (JP) 2024-11-28 — — US disclosed
US-12103947-B2 Methods for producing peptide thioester and peptide GLYTECH, INC. (JP) 2024-10-01 — — US disclosed
US-20230143844-A1 NOVEL METHODS FOR PRODUCING PEPTIDE THIOESTER AND PEPTIDE GLYTECH, INC. (JP) 2023-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143844-A1 NOVEL METHODS FOR PRODUCING PEPTIDE THIOESTER AND PEPTIDE QPCT, PTMS, QPCTL OPRD1 4547/4885OPRM1 4795/4885OPRK1 4579/4885
US-12103947-B2 Methods for producing peptide thioester and peptide QPCT, QPCTL, PTMS OPRD1 4532/4885OPRM1 4791/4885OPRK1 4536/4885
US-20240391951-A1 NOVEL METHODS FOR PRODUCING PEPTIDE THIOESTER AND PEPTIDE QPCT, PTMS, QPCTL OPRD1 4547/4885OPRM1 4795/4885OPRK1 4579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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