SCHEMBL30407736

SCHEMBL30407736

O=C(O)CCCNC(=O)C(NC(=O)OCc1ccccc1)C(NC(=O)OCc1ccccc1)C(=O)NCCOCCOCCOCCOCCC(=O)OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 2/20 0.57
▸ SMN1; SMN2 Q16637 2/20 0.53
▸ LMNA P02545 1/20 0.53
▸ CAPN1 P07384 1/20 0.47
▸ CAPN2 P17655 1/20 0.47
▸ SIRT5 Q9NXA8 2/20 0.46
▸ CTSL P07711 2/20 0.46
▸ CTSS P25774 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ HPGD P15428 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ FOLH1 Q04609 2/20 0.45
▸ MME P08473 1/20 0.45
▸ ECE1 P42892 1/20 0.45
▸ EPOR P19235 3/20 0.45
▸ CTSB P07858 1/20 0.44
▸ CA2 P00918 1/20 0.44
▸ CA5A P35218 1/20 0.44
▸ CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29467716 0.96 HTT (0.53) HTTSMN1; SMN2LMNACAPN1CAPN2
SCHEMBL29467703 0.90 HTT (0.57) HTTSMN1; SMN2LMNACAPN1CAPN2
SCHEMBL30407162 0.89 SMN1; SMN2 (0.47) HTTSMN1; SMN2LMNACAPN1CAPN2
SCHEMBL23451325 0.88 HTT (0.72) HTTCAPN1CAPN2SIRT5CTSL
SCHEMBL23451326 0.88 HTT (0.72) HTTCAPN1CAPN2SIRT5CTSL
SCHEMBL30407627 0.87 SMN1; SMN2 (0.46) HTTSMN1; SMN2LMNACAPN1CAPN2
SCHEMBL29467718 0.86 CAPN1 (0.47) HTTSMN1; SMN2LMNACAPN1CAPN2
SCHEMBL29467632 0.84 CAPN1 (0.45) HTTSMN1; SMN2LMNACAPN1CAPN2
SCHEMBL29467638 0.81 SMN1; SMN2 (0.47) HTTSMN1; SMN2LMNACAPN1CAPN2
SCHEMBL29548496 0.81 SMN1; SMN2 (0.47) HTTSMN1; SMN2LMNACAPN1CAPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4426741-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE Hangzhou DAC Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
EP-4426729-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
WO-2023078021-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
WO-2023078273-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 — — WO disclosed
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