Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | EPOR | P19235 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30407627 | 0.97 | SMN1; SMN2 (0.46) | CAPN1CAPN2LMNASMN1; SMN2MEN1 | |
| SCHEMBL29467710 | 0.90 | SMN1; SMN2 (0.46) | CAPN1CAPN2LMNASMN1; SMN2SIRT2 | |
| SCHEMBL29467716 | 0.88 | HTT (0.53) | CAPN1CAPN2LMNASMN1; SMN2SIRT2 | |
| SCHEMBL29467718 | 0.87 | CAPN1 (0.47) | CAPN1CAPN2LMNASMN1; SMN2SIRT2 | |
| SCHEMBL27438957 | 0.86 | LMNA (0.47) | LMNASMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL27438917 | 0.86 | LMNA (0.47) | LMNASMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL20577215 | 0.84 | LMNA (0.47) | LMNASMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL30407736 | 0.84 | HTT (0.57) | CAPN1CAPN2LMNASMN1; SMN2MEN1 | |
| SCHEMBL30407162 | 0.83 | SMN1; SMN2 (0.47) | CAPN1CAPN2LMNASMN1; SMN2MEN1 | |
| SCHEMBL25331392 | 0.81 | SMN1; SMN2 (0.49) | CAPN1CAPN2LMNASMN1; SMN2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426727-A2 | SPECIFIC CONJUGATION OF AN ANTIBODY | Hangzhou Dac Biotech Co., Ltd. (CN) | 2024-09-11 | — | — | EP | disclosed |
| WO-2022078524-A4 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022078524-A2 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |