Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 13/20 | 0.59 |
| ▸ | TTBK1 | Q5TCY1 | 4/20 | 0.54 |
| ▸ | TTBK2 | Q6IQ55 | 4/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30408294 | 0.82 | JAK2 (0.55) | JAK2TTBK1TTBK2TRPA1 | |
| SCHEMBL30564544 | 0.79 | TRPA1 (0.75) | TTBK1TTBK2TRPA1 | |
| SCHEMBL2882091 | 0.79 | TRPA1 (0.75) | TTBK1TTBK2TRPA1 | |
| SCHEMBL7958023 | 0.77 | HRH4 (0.45) | JAK2TTBK1TTBK2TRPA1 | |
| SCHEMBL30408533 | 0.76 | JAK2 (1.00) | JAK2TTBK1TTBK2 | |
| SCHEMBL30408846 | 0.75 | JAK2 (1.00) | JAK2TTBK1TTBK2 | |
| SCHEMBL30407944 | 0.75 | JAK2 (0.66) | JAK2TTBK1TTBK2 | |
| SCHEMBL30408025 | 0.74 | JAK2 (0.71) | JAK2TTBK1TTBK2 | |
| SCHEMBL30408840 | 0.74 | JAK2 (0.88) | JAK2TTBK1TTBK2 | |
| SCHEMBL24881187 | 0.71 | TTBK1 (1.00) | TTBK1TTBK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064458-A1 | SELECTIVE JAK2 INHIBITORS AND METHODS OF USE | YALE UNIVERSITY (US) | 2023-04-20 | — | — | WO | disclosed |