Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23440772 | 1.00 | ALDH1A1 (0.66) | ALDH1A1TDP1POLBRXFP1L3MBTL1 | |
| SCHEMBL21647792 | 0.90 | ALDH1A1 (0.56) | ALDH1A1TDP1POLBRXFP1L3MBTL1 | |
| SCHEMBL10960723 | 0.87 | ALDH1A1 (0.71) | ALDH1A1TDP1POLBMAPTLMNA | |
| SCHEMBL8663614 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TDP1POLBMAPTLMNA | |
| SCHEMBL8186954 | 0.81 | ALDH1A1 (1.00) | ALDH1A1TDP1POLBL3MBTL1MAPT | |
| SCHEMBL14291659 | 0.81 | MEN1 (0.76) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL14605920 | 0.79 | MAPT (0.54) | ALDH1A1TDP1POLBMAPTLMNA | |
| SCHEMBL14133293 | 0.79 | MEN1 (0.77) | ALDH1A1TDP1POLBMAPTLMNA | |
| SCHEMBL14063592 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TDP1POLBMAPTLMNA | |
| SCHEMBL11009733 | 0.77 | CYP1A2 (0.70) | ALDH1A1POLBMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513011-B | Benzene derivatives | 小野药品工业株式会社 | 2023-06-16 | — | — | CN | disclosed |