Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24216692 | 1.00 | HDAC6 (0.40) | HDAC6HDAC1LRRK2 | |
| SCHEMBL24216081 | 0.86 | TEK (0.47) | HDAC6HDAC1 | |
| SCHEMBL30409885 | 0.86 | TEK (0.47) | HDAC6HDAC1 | |
| SCHEMBL25350410 | 0.86 | HDAC6 (0.45) | HDAC6HDAC1 | |
| SCHEMBL25354688 | 0.85 | HDAC6 (0.41) | HDAC6HDAC1LRRK2 | |
| SCHEMBL30409209 | 0.85 | HDAC6 (0.41) | HDAC6HDAC1LRRK2 | |
| SCHEMBL25992736 | 0.83 | HDAC6 (0.43) | HDAC6HDAC1 | |
| SCHEMBL30409440 | 0.83 | HDAC1 (0.48) | HDAC6HDAC1 | |
| SCHEMBL24215834 | 0.83 | HDAC1 (0.48) | HDAC6HDAC1 | |
| SCHEMBL25213743 | 0.83 | HDAC6 (0.42) | HDAC6HDAC1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |