Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24215834 | 1.00 | HDAC1 (0.48) | HDAC1HDAC6DPP4CYP19A1ROCK2 | |
| SCHEMBL25351646 | 0.91 | DPP4 (0.48) | HDAC1HDAC6DPP4ROCK2GSK3B | |
| SCHEMBL25350410 | 0.90 | HDAC6 (0.45) | HDAC1HDAC6ROCK2PAK4PIM1 | |
| SCHEMBL24215788 | 0.90 | HDAC1 (0.42) | HDAC1HDAC6ROCK2PAK4PIM1 | |
| SCHEMBL30410054 | 0.90 | HDAC1 (0.42) | HDAC1HDAC6ROCK2PAK4PIM1 | |
| SCHEMBL30409885 | 0.89 | TEK (0.47) | HDAC1HDAC6ROCK2PAK4PIM1 | |
| SCHEMBL25992738 | 0.89 | TEK (0.47) | HDAC1HDAC6ROCK2PAK4PIM1 | |
| SCHEMBL24216081 | 0.89 | TEK (0.47) | HDAC1HDAC6ROCK2PAK4PIM1 | |
| SCHEMBL25351083 | 0.89 | ALOX5 (0.48) | HDAC1HDAC6ALOX5PTGES2 | |
| SCHEMBL25352081 | 0.89 | HDAC6 (0.49) | HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |