Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677639 | 0.78 | CSNK2A1 (0.50) | MAPTPOLBALDH1A1NPSR1KMT2A | |
| SCHEMBL30409659 | 0.77 | EPHX2 (0.61) | EPHX2MAPTPOLBLMNAALDH1A1 | |
| SCHEMBL30409232 | 0.77 | EPHX2 (0.71) | EPHX2HDAC1HDAC8HDAC6CA12 | |
| Hydrochloric Acid SCHEMBL5067692 | 0.77 | CSNK2A1 (0.49) | MAPTPOLBALDH1A1NPSR1KMT2A | |
| Hydrochloric Acid SCHEMBL5065548 | 0.77 | CSNK2A1 (0.49) | MAPTPOLBALDH1A1NPSR1KMT2A | |
| SCHEMBL1725459 | 0.75 | TOP2B (0.53) | TOP2BHDAC1MAPTLMNAALDH1A1 | |
| SCHEMBL30409629 | 0.72 | HDAC1 (0.58) | HDAC1HDAC8HDAC6MAPTALDH1A1 | |
| SCHEMBL1726083 | 0.72 | MAPT (0.62) | TOP2BMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL5068037 | 0.72 | BRD4 (0.40) | TOP2BMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL1923881 | 0.71 | HDAC8 (0.63) | TOP2BHDAC1HDAC8HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102525-B | Benzamide derivatives and uses thereof | 沈阳药科大学 | 2024-11-12 | — | — | CN | disclosed |
| CN-116102525-A | Benzamide derivatives and uses thereof | 沈阳药科大学 | 2023-05-12 | — | — | CN | disclosed |