Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25176593 | 0.95 | TSHR (0.54) | TSHRHTTTDP1HSD17B10GLA | |
| SCHEMBL1953902 | 0.90 | TSHR (0.57) | TSHRTDP1KMT2AMEN1EZH2 | |
| SCHEMBL30409767 | 0.90 | TSHR (0.57) | TSHRTDP1KMT2AMEN1EZH2 | |
| SCHEMBL982145 | 0.86 | TSHR (0.59) | TSHRTDP1KMT2AMEN1EZH2 | |
| SCHEMBL29914212 | 0.86 | TSHR (0.59) | TSHRTDP1KMT2AMEN1EZH2 | |
| SCHEMBL15482368 | 0.85 | TSHR (0.53) | TSHRHTTTDP1KMT2AMEN1 | |
| SCHEMBL1022340 | 0.84 | TSHR (0.60) | TSHRHTTTDP1EZH2SMN1; SMN2 | |
| SCHEMBL15093963 | 0.84 | TSHR (0.52) | TSHRHTTTDP1KMT2AMEN1 | |
| SCHEMBL29914217 | 0.84 | TSHR (0.52) | TSHRHTTTDP1KMT2AMEN1 | |
| SCHEMBL1021679 | 0.82 | TSHR (0.60) | TSHRHTTTDP1HSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023080257-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION | 旭化成株式会社 | 2023-05-11 | — | — | WO | disclosed |