Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15093963 | 1.00 | TSHR (0.52) | TSHREZH2TDP1KMT2AMEN1 | |
| SCHEMBL30409767 | 0.93 | TSHR (0.57) | TSHREZH2TDP1KMT2AMEN1 | |
| SCHEMBL1953902 | 0.93 | TSHR (0.57) | TSHREZH2TDP1KMT2AMEN1 | |
| SCHEMBL990889 | 0.90 | TSHR (0.54) | TSHREZH2TDP1KMT2AMEN1 | |
| SCHEMBL15482368 | 0.90 | TSHR (0.53) | TSHREZH2TDP1KMT2AMEN1 | |
| SCHEMBL29914212 | 0.85 | TSHR (0.59) | TSHREZH2TDP1KMT2AMEN1 | |
| SCHEMBL982145 | 0.85 | TSHR (0.59) | TSHREZH2TDP1KMT2AMEN1 | |
| SCHEMBL30409019 | 0.84 | TSHR (0.58) | TSHREZH2TDP1KMT2AMEN1 | |
| SCHEMBL29840056 | 0.83 | TSHR (0.39) | TSHREZH2KMT2AALDH1A1GAA | |
| SCHEMBL6526426 | 0.82 | TSHR (0.55) | TSHREZH2TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838892-B1 | METHOD FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2022-10-12 | — | — | EP | disclosed |