Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.52 |
| ▸ | TEK | Q02763 | 10/20 | 0.45 |
| ▸ | KDR | P35968 | 9/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24215760 | 1.00 | HDAC6 (0.52) | HDAC6TEKKDREPHB4NPC1 | |
| SCHEMBL25218954 | 0.89 | HDAC6 (0.58) | HDAC6TEKKDREPHB4NPC1 | |
| SCHEMBL25992740 | 0.87 | TEK (0.61) | HDAC6TEKKDREPHB4NPC1 | |
| SCHEMBL30409407 | 0.87 | HDAC1 (0.47) | HDAC6HDAC1 | |
| SCHEMBL30409948 | 0.87 | HDAC6 (0.55) | HDAC6HDAC1 | |
| SCHEMBL24216473 | 0.87 | HDAC6 (0.55) | HDAC6HDAC1 | |
| SCHEMBL24216445 | 0.87 | HDAC1 (0.47) | HDAC6HDAC1 | |
| SCHEMBL30409508 | 0.86 | HDAC6 (0.55) | HDAC6TEKKDREPHB4NPC1 | |
| SCHEMBL25216837 | 0.86 | HDAC6 (0.55) | HDAC6TEKKDREPHB4CYP19A1 | |
| SCHEMBL24216740 | 0.86 | HDAC6 (0.55) | HDAC6TEKKDREPHB4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |