Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 10/20 | 0.61 |
| ▸ | KDR | P35968 | 10/20 | 0.61 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25992735 | 0.90 | HDAC6 (0.57) | TEKKDREPHB4HDAC6NPC1 | |
| SCHEMBL25216837 | 0.88 | HDAC6 (0.55) | TEKKDREPHB4HDAC6ROCK2 | |
| SCHEMBL30409508 | 0.88 | HDAC6 (0.55) | TEKKDREPHB4HDAC6NPC1 | |
| SCHEMBL24216740 | 0.88 | HDAC6 (0.55) | TEKKDREPHB4HDAC6NPC1 | |
| SCHEMBL30410153 | 0.88 | TEK (0.61) | TEKKDREPHB4HDAC6NPC1 | |
| SCHEMBL25254106 | 0.88 | TEK (0.61) | TEKKDREPHB4HDAC6NPC1 | |
| SCHEMBL24215760 | 0.87 | HDAC6 (0.52) | TEKKDREPHB4HDAC6NPC1 | |
| SCHEMBL30409054 | 0.87 | HDAC6 (0.52) | TEKKDREPHB4HDAC6NPC1 | |
| SCHEMBL24215835 | 0.87 | HDAC6 (0.62) | TEKKDREPHB4HDAC6NPC1 | |
| SCHEMBL31535159 | 0.86 | HDAC6 (0.57) | TEKKDREPHB4HDAC6ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257372-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257372-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HDAC6, HDAC1, HDAC3 | TEK 3885/4885KDR 4706/4885EPHB4 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.