Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.53 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509469 | 1.00 | KDM1A (0.53) | KDM1AKDM1BALDH1A1DGAT1DPP4 | |
| SCHEMBL1592114 | 0.85 | KDM1A (0.41) | KDM1AKDM1BALDH1A1DGAT1DPP4 | |
| SCHEMBL5040961 | 0.80 | HTR2C (0.47) | KDM1AKDM1BALDH1A1MAPT | |
| SCHEMBL12609570 | 0.78 | KDM1A (0.55) | KDM1AKDM1BALDH1A1DGAT1DPP4 | |
| SCHEMBL12609563 | 0.78 | KDM1A (0.55) | KDM1AKDM1BALDH1A1DGAT1DPP4 | |
| SCHEMBL25386684 | 0.77 | KDM1A (0.39) | KDM1AKDM1BMAPT | |
| SCHEMBL31562913 | 0.77 | ALOX15 (0.39) | KDM1AKDM1BALDH1A1MAPTLMNA | |
| SCHEMBL25384149 | 0.77 | ALOX15 (0.39) | KDM1AKDM1BALDH1A1MAPTLMNA | |
| SCHEMBL3830652 | 0.77 | HTT (0.39) | KDM1AKDM1BALDH1A1NPC1RAB9A | |
| SCHEMBL25385154 | 0.77 | KDM1A (0.34) | KDM1AKDM1BMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |