Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 11/20 | 0.65 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.65 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | CDK9 | P50750 | 2/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.53 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.53 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.53 |
| ▸ | ATP1A1 | P05023 | 3/20 | 0.50 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.50 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.50 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.50 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.50 |
| ▸ | ATP1B3 | P54709 | 3/20 | 0.50 |
| ▸ | FXYD2 | P54710 | 3/20 | 0.50 |
| ▸ | ATP1A4 | Q13733 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039694 | 1.00 | FYN (0.65) | FYNMKNK1DYRK3CCNT1CCNA2 | |
| SCHEMBL16622975 | 0.85 | FYN (0.65) | FYN | |
| SCHEMBL3034130 | 0.84 | FYN (0.65) | FYNMKNK1DYRK3CCNT1CCNA2 | |
| SCHEMBL3043616 | 0.84 | FYN (0.65) | FYNMKNK1DYRK3CCNT1CCNA2 | |
| SCHEMBL19308430 | 0.82 | FYN (0.49) | FYNMKNK1DYRK3CCNT1CCNA2 | |
| SCHEMBL19263570 | 0.82 | FYN (0.51) | FYNMKNK1DYRK3CCNT1CCNA2 | |
| SCHEMBL3049721 | 0.81 | FYN (0.71) | FYNMKNK1DYRK3CCNT1CCNA2 | |
| SCHEMBL3043393 | 0.81 | FYN (0.71) | FYNMKNK1DYRK3CCNT1CCNA2 | |
| SCHEMBL9902335 | 0.80 | FYN (0.46) | FYNMKNK1DYRK3CCNT1CCNA2 | |
| SCHEMBL16468560 | 0.79 | PLK1 (0.45) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216798-A1 | FUSED HETEROCYCLES AS LCK INHIBITORS | ASTELLAS PHARMA INC (JP) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216798-A1 | FUSED HETEROCYCLES AS LCK INHIBITORS | LCK, ZAP70, FYN | FYN 3/4885MKNK1 816/4885DYRK3 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.