Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.36 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24215733 | 1.00 | HDAC6 (0.47) | HDAC6HDAC1ROCK2GSK3BAURKA | |
| SCHEMBL25350464 | 0.93 | HDAC6 (0.47) | HDAC6HDAC1ROCK2GSK3BAURKA | |
| SCHEMBL25352086 | 0.87 | HDAC6 (0.53) | HDAC6ROCK2GSK3BAURKAPRKCG | |
| SCHEMBL25352046 | 0.86 | HDAC6 (0.52) | HDAC6HDAC1ROCK2GSK3BPIM1 | |
| SCHEMBL31535155 | 0.86 | HDAC6 (0.48) | HDAC6ROCK2GSK3BAURKAPRKCG | |
| SCHEMBL25350786 | 0.86 | HDAC6 (0.48) | HDAC6ROCK2GSK3BAURKAPRKCG | |
| SCHEMBL25350896 | 0.85 | HDAC6 (0.52) | HDAC6ROCK2GSK3BAURKAPRKCG | |
| SCHEMBL25211647 | 0.83 | HDAC6 (0.50) | HDAC6HDAC1ROCK2GSK3BPIM1 | |
| SCHEMBL25216550 | 0.83 | HDAC6 (0.47) | HDAC6HDAC1ROCK2GSK3BPIM1 | |
| SCHEMBL30424865 | 0.83 | HDAC6 (0.50) | HDAC6HDAC1ROCK2GSK3BPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |