Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 10/20 | 0.46 |
| ▸ | GSK3B | P49841 | 10/20 | 0.46 |
| ▸ | PIM1 | P11309 | 7/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.46 |
| ▸ | CDC7 | O00311 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | PRKCG | P05129 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 2/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.46 |
| ▸ | SGK2 | Q9HBY8 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31535155 | 1.00 | HDAC6 (0.48) | HDAC6ROCK2GSK3BPIM1AURKB | |
| SCHEMBL25351342 | 0.93 | ROCK2 (0.56) | HDAC6ROCK2GSK3BPIM1AURKB | |
| SCHEMBL25352046 | 0.88 | HDAC6 (0.52) | HDAC6ROCK2GSK3BPIM1AURKB | |
| SCHEMBL25268143 | 0.88 | ROCK2 (0.58) | HDAC6ROCK2GSK3BPIM1AURKB | |
| SCHEMBL30425892 | 0.88 | ROCK2 (0.58) | HDAC6ROCK2GSK3BPIM1AURKB | |
| SCHEMBL25351235 | 0.87 | ROCK2 (0.47) | HDAC6ROCK2GSK3BPIM1AURKB | |
| SCHEMBL30409995 | 0.86 | HDAC6 (0.47) | HDAC6ROCK2GSK3BPIM1AURKB | |
| SCHEMBL24215733 | 0.86 | HDAC6 (0.47) | HDAC6ROCK2GSK3BPIM1AURKB | |
| SCHEMBL25349809 | 0.85 | ROCK2 (0.55) | HDAC6ROCK2GSK3BPIM1AURKB | |
| SCHEMBL31535157 | 0.85 | ROCK2 (0.55) | HDAC6ROCK2GSK3BPIM1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257372-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-17 | — | — | US | disclosed |
| US-20230257372-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-17 | — | — | US | disclosed |
| US-20230257372-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257372-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HDAC6, HDAC1, HDAC3 | HDAC6 1/4885ROCK2 2366/4885GSK3B 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.