Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 12/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 11/20 | 0.35 |
| ▸ | HTR2A | P28223 | 10/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.30 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25138136 | 0.76 | CRBN (0.42) | — | |
| SCHEMBL2333387 | 0.69 | HTR2B (0.49) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL30410731 | 0.67 | HTR2B (0.40) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL30496975 | 0.67 | PARP1 (0.50) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL30410655 | 0.65 | HTR2B (0.47) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL30496990 | 0.61 | PARP1 (0.45) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL30496977 | 0.61 | PARP1 (0.45) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL30460068 | 0.60 | HTR2B (0.49) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL25235039 | 0.60 | HTR2B (0.49) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL30132224 | 0.60 | HTR2B (0.49) | HTR2BHTR3EHTR3BHTR3ATMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061478-A1 | TRICYCLIC COMPOUND | 先声再明医药有限公司 | 2023-04-20 | — | — | WO | disclosed |