Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12488931 | 1.00 | GAA (0.43) | GAAKDM4EALDH1A1HPGDCRHBP | |
| SCHEMBL19559116 | 0.89 | KDM4E (0.46) | GAAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL18432591 | 0.84 | PDGFRB (0.43) | GAAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12489156 | 0.81 | PDGFRB (0.40) | GAAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12488184 | 0.79 | GAA (0.47) | GAAKDM4EALDH1A1HPGDCRHBP | |
| SCHEMBL31312529 | 0.79 | GAA (0.47) | GAAKDM4EALDH1A1HPGDCRHBP | |
| SCHEMBL28974072 | 0.78 | KDM4E (0.41) | GAAKDM4EALDH1A1HPGDCRHBP | |
| SCHEMBL21451503 | 0.78 | PDGFRB (0.38) | KDM4EALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL30280685 | 0.78 | PDGFRB (0.38) | GAAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12489199 | 0.78 | PDGFRB (0.38) | GAAKDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |