Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280859 | 0.79 | PTGER4 (0.43) | KDM4EALDH1A1HPGDCRHBPCRHR2 | |
| SCHEMBL30410282 | 0.78 | GAA (0.43) | KDM4EALDH1A1HPGDGAACRHBP | |
| SCHEMBL12488931 | 0.78 | GAA (0.43) | KDM4EALDH1A1HPGDGAACRHBP | |
| SCHEMBL28974061 | 0.76 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDGAACRHBP | |
| SCHEMBL28974054 | 0.71 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDGAACRHBP | |
| SCHEMBL28974078 | 0.70 | LMNA (0.50) | KDM4EALDH1A1HPGDGAACRHBP | |
| SCHEMBL12488184 | 0.69 | GAA (0.47) | KDM4EALDH1A1HPGDGAACRHBP | |
| SCHEMBL31312529 | 0.69 | GAA (0.47) | KDM4EALDH1A1HPGDGAACRHBP | |
| SCHEMBL30280919 | 0.69 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL30281005 | 0.69 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDGAARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |