Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30410640 | 0.95 | NPC1 (0.56) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30411079 | 0.92 | NPC1 (0.53) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30410990 | 0.90 | NPC1 (0.51) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30410654 | 0.90 | CTSL (0.54) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30411049 | 0.90 | NPC1 (0.51) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30410705 | 0.90 | NPC1 (0.51) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30410355 | 0.90 | NPC1 (0.51) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30410406 | 0.89 | NPC1 (0.63) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30410754 | 0.88 | NPC1 (0.49) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30409928 | 0.87 | NPC1 (0.57) | ADORA3ADORA2AADORA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4178959-A1 | NITROGEN HETEROCYCLIC CYTOKININ DERIVATIVES, COMPOSITIONS CONTAINING THESE DERIVATIVES AND USE THEREOF | Univerzita Palackého v Olomouci (CZ) | 2023-05-17 | — | — | EP | disclosed |