Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767101 | 1.00 | KIF11 (0.45) | KIF11TEAD1TEAD4TEAD2DHODH | |
| SCHEMBL20552318 | 0.84 | LRRK2 (0.50) | KIF11TEAD1TEAD4TEAD2DHODH | |
| SCHEMBL20552520 | 0.82 | KIF11 (0.45) | KIF11TEAD1TEAD4TEAD2DHODH | |
| SCHEMBL20553084 | 0.82 | SLC22A12 (0.47) | KIF11TEAD1TEAD4TEAD2DHODH | |
| SCHEMBL20552788 | 0.82 | LRRK2 (0.49) | KIF11TEAD1TEAD4TEAD2DHODH | |
| SCHEMBL20552334 | 0.79 | TRPV1 (0.44) | KIF11TEAD1TEAD4TEAD2DHODH | |
| SCHEMBL20553063 | 0.79 | LRRK2 (0.52) | KIF11TEAD1TEAD4TEAD2DHODH | |
| SCHEMBL20553187 | 0.78 | TEAD1 (0.53) | KIF11TEAD1TEAD4TEAD2DHODH | |
| SCHEMBL26665296 | 0.77 | MAPT (0.43) | KIF11TEAD1DHODHKDM4EMEN1 | |
| SCHEMBL20552937 | 0.77 | MEN1 (0.43) | KIF11TEAD1TEAD4TEAD2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542315-B | Benzosulfonyl compounds | 维瓦斯治疗公司 | 2023-05-12 | — | — | CN | disclosed |