Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23991294 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAMAPTNPSR1POLB | |
| SCHEMBL23991457 | 0.90 | LMNA (0.35) | SMN1; SMN2LMNANCOA3NPC1MEN1 | |
| SCHEMBL30411728 | 0.90 | LMNA (0.35) | SMN1; SMN2LMNANCOA3NPC1MEN1 | |
| SCHEMBL23991802 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAMAPTNPSR1POLB | |
| SCHEMBL30411399 | 0.86 | MEN1 (0.39) | MAPTNPC1MEN1KMT2ARAB9A | |
| SCHEMBL23991795 | 0.86 | MEN1 (0.39) | MAPTNPC1MEN1KMT2ARAB9A | |
| SCHEMBL30410698 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAMAPTNPSR1POLB | |
| SCHEMBL23991581 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAMAPTNPSR1POLB | |
| SCHEMBL23991323 | 0.85 | MEN1 (0.35) | POLBNPC1MEN1CYP1A2CYP2C9 | |
| SCHEMBL30411881 | 0.85 | MEN1 (0.35) | POLBNPC1MEN1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143197-A1 | THIENO PYRIMIDINES AS FERROPORTIN INHIBITORS | Global Blood Therapeutics, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |