Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29012685 | 1.00 | CCR3 (0.53) | CCR3MEN1KMT2ATP53HTT | |
| SCHEMBL30414968 | 0.89 | CCR3 (0.49) | CCR3KMT2A | |
| SCHEMBL29012676 | 0.89 | CCR3 (0.49) | CCR3KMT2A | |
| SCHEMBL29012688 | 0.87 | CCR3 (0.48) | CCR3FAAH | |
| SCHEMBL30414210 | 0.87 | CCR3 (0.48) | CCR3FAAH | |
| SCHEMBL29012670 | 0.85 | CCR3 (0.51) | CCR3 | |
| SCHEMBL30413472 | 0.85 | CCR3 (0.51) | CCR3 | |
| SCHEMBL29012696 | 0.81 | TSHR (0.62) | CCR3TP53HTTTSHRACKR3 | |
| SCHEMBL30414906 | 0.81 | TSHR (0.62) | CCR3TP53HTTTSHRACKR3 | |
| SCHEMBL29012681 | 0.81 | CCR3 (0.49) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217543-A | Novel CCR3 inhibitor compound and application thereof | 成都康弘药业集团股份有限公司 | 2023-06-06 | — | — | CN | disclosed |