Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | CCR3 | P51677 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29012696 | 1.00 | TSHR (0.62) | TSHRCCR3TP53HTTL3MBTL1 | |
| SCHEMBL29012683 | 0.90 | NR2F2 (0.49) | TSHRCCR3 | |
| SCHEMBL30413973 | 0.90 | NR2F2 (0.49) | TSHRCCR3 | |
| SCHEMBL30414968 | 0.82 | CCR3 (0.49) | CCR3 | |
| SCHEMBL29012676 | 0.82 | CCR3 (0.49) | CCR3 | |
| SCHEMBL30414213 | 0.81 | CCR3 (0.53) | TSHRCCR3TP53HTTACKR3 | |
| SCHEMBL29012685 | 0.81 | CCR3 (0.53) | TSHRCCR3TP53HTTACKR3 | |
| SCHEMBL29012688 | 0.80 | CCR3 (0.48) | CCR3 | |
| SCHEMBL30414210 | 0.80 | CCR3 (0.48) | CCR3 | |
| SCHEMBL29012681 | 0.80 | CCR3 (0.49) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217543-A | Novel CCR3 inhibitor compound and application thereof | 成都康弘药业集团股份有限公司 | 2023-06-06 | — | — | CN | disclosed |