SCHEMBL30415249

SCHEMBL30415249

Clc1cc(Br)nc(Cl)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18381558 1.00
SCHEMBL30725538 0.85
SCHEMBL218052 0.78
Ammonia Solution, Strong SCHEMBL27915759 0.78 ALDH1A1 (0.50)
SCHEMBL25357793 0.78
SCHEMBL30626416 0.78
SCHEMBL29267478 0.74
SCHEMBL31607155 0.72
SCHEMBL32457366 0.72
SCHEMBL30547157 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116134022-B ATR inhibitors and uses thereof 上海德琪医药科技有限公司 2025-03-18 CN disclosed
CN-116478098-A Polyimide precursor, polyimide, preparation method and application thereof 深圳先进电子材料国际创新研究院 2023-07-25 CN disclosed
CN-116134022-A ATR inhibitors and uses thereof 上海德琪医药科技有限公司 2023-05-16 CN disclosed
EP-4175948-A1 ATR INHIBITORS AND USES THEREOF ANTENGENE DISCOVERY LIMITED (CN) 2023-05-10 EP disclosed