Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB3 | P21860 | 1/20 | 0.58 |
| ▸ | BTK | Q06187 | 16/20 | 0.56 |
| ▸ | EGFR | P00533 | 4/20 | 0.56 |
| ▸ | LCK | P06239 | 4/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | TEK | Q02763 | 1/20 | 0.55 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.54 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.54 |
| ▸ | ITK | Q08881 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | HCK | P08631 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.53 |
| ▸ | PRKDC | P78527 | 1/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196637 | 1.00 | ERBB3 (0.58) | ERBB3BTKEGFRLCKSRC | |
| SCHEMBL24197244 | 0.97 | BTK (0.59) | ERBB3BTKEGFRLCKSRC | |
| SCHEMBL24196643 | 0.96 | ERBB3 (0.56) | ERBB3BTKEGFRLCKSRC | |
| SCHEMBL24196640 | 0.95 | BTK (0.57) | ERBB3BTKEGFRLCKSRC | |
| SCHEMBL24192712 | 0.94 | BTK (0.55) | ERBB3BTKEGFRLCKSRC | |
| SCHEMBL18123563 | 0.93 | BTK (0.61) | BTKEGFRLCKITKKIT | |
| SCHEMBL30416245 | 0.91 | BTK (0.57) | BTKEGFRLCKSRCKDR | |
| SCHEMBL24196614 | 0.91 | BTK (0.57) | BTKEGFRLCKSRCKDR | |
| SCHEMBL22720717 | 0.90 | BTK (0.69) | BTKEGFRLCKSRCKDR | |
| SCHEMBL22720698 | 0.90 | BTK (0.69) | BTKEGFRLCKSRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134028-A | Compound capable of degrading BTK kinase, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-05-16 | — | — | CN | disclosed |