Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.45 |
| ▸ | SMPD3 | Q9NY59 | 4/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636961 | 0.82 | CYP1A2 (0.49) | NNMT | |
| SCHEMBL11635317 | 0.81 | CYP1A2 (0.51) | NNMT | |
| SCHEMBL22042049 | 0.78 | ACKR3 (0.45) | ACKR3 | |
| SCHEMBL22042051 | 0.78 | ACKR3 (0.45) | ACKR3 | |
| SCHEMBL30415191 | 0.77 | HDAC6 (0.44) | IKBKBSMPD3CHUKSMARCA2SMARCA4 | |
| SCHEMBL11908194 | 0.77 | SMPD3 (0.44) | IKBKBSMPD3SMARCA2SMARCA4PBRM1 | |
| SCHEMBL18291469 | 0.77 | SMPD3 (0.44) | IKBKBSMPD3SMARCA2SMARCA4PBRM1 | |
| SCHEMBL20255217 | 0.77 | SMPD3 (0.44) | IKBKBSMPD3SMARCA2SMARCA4PBRM1 | |
| SCHEMBL31200769 | 0.77 | CYP1A2 (0.60) | SMPD3 | |
| Ethane SCHEMBL27296723 | 0.75 | SMPD3 (0.43) | IKBKBSMPD3SMARCA2SMARCA4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598858-A | Multifunctional compound, composition and application of degradable BTK kinase | 杭州和正医药有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-116143757-B | Multifunctional compound, composition and application of degradable BTK kinase | 杭州和正医药有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-116143757-A | Multifunctional compound, composition and application of degradable BTK kinase | 杭州和正医药有限公司 | 2023-05-23 | — | — | CN | disclosed |