Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 2/20 | 0.39 |
| ▸ | CAMK1D | Q8IU85 | 10/20 | 0.38 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.38 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.36 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.36 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.36 |
| ▸ | PNCK | Q6P2M8 | 1/20 | 0.36 |
| ▸ | CAMK1G | Q96NX5 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30416836 | 0.92 | AOC3 (0.43) | HDAC6IKBKBAOC3HRH3 | |
| SCHEMBL30416706 | 0.83 | HDAC6 (0.53) | HDAC6IKBKBCAMK1DSMPD3PIP5K1C | |
| SCHEMBL30416847 | 0.81 | ALDH1A1 (0.46) | HDAC6CYP2C9CYP2C19AOC3 | |
| SCHEMBL30165824 | 0.80 | BTK (0.37) | CAMK1DPIP5K1CCYP2C9CYP2C19RIPK4 | |
| SCHEMBL30160759 | 0.78 | JAK3 (0.52) | — | |
| SCHEMBL30160681 | 0.78 | JAK3 (0.52) | — | |
| SCHEMBL30416158 | 0.77 | IKBKB (0.45) | IKBKBSMPD3CHUKSMARCA2SMARCA4 | |
| SCHEMBL31052385 | 0.76 | LCK (0.35) | CAMK1DPIP5K1CCYP2C9CYP2C19RIPK4 | |
| SCHEMBL31052405 | 0.76 | LCK (0.35) | CAMK1DPIP5K1CCYP2C9CYP2C19RIPK4 | |
| SCHEMBL31052397 | 0.74 | LCK (0.33) | CAMK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598858-A | Multifunctional compound, composition and application of degradable BTK kinase | 杭州和正医药有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-116143757-B | Multifunctional compound, composition and application of degradable BTK kinase | 杭州和正医药有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-116143757-A | Multifunctional compound, composition and application of degradable BTK kinase | 杭州和正医药有限公司 | 2023-05-23 | — | — | CN | disclosed |