Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 5/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | RAMP3 | O60896 | 7/20 | 0.41 |
| ▸ | CALCR | P30988 | 7/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29827418 | 1.00 | CALCRL (0.46) | CALCRLMAPK8MAPK9MAPK10RAMP3 | |
| SCHEMBL29977789 | 0.87 | MAPK8 (0.46) | CALCRLMAPK8MAPK9MAPK10PTPN1 | |
| SCHEMBL30582212 | 0.85 | MAPK8 (0.47) | MAPK8MAPK9MAPK10PTPN1 | |
| SCHEMBL30311197 | 0.82 | MAPK8 (0.43) | CALCRLMAPK8MAPK9MAPK10 | |
| SCHEMBL30311186 | 0.81 | MAPK8 (0.42) | CALCRLMAPK8MAPK9MAPK10 | |
| SCHEMBL29416074 | 0.80 | CALCRL (0.45) | CALCRLMAPK8MAPK9MAPK10 | |
| SCHEMBL30311202 | 0.80 | ACE (0.52) | MAPK8MAPK9MAPK10 | |
| SCHEMBL31410825 | 0.80 | MAPK8 (0.56) | MAPK8MAPK9MAPK10RAMP3CALCR | |
| SCHEMBL31001016 | 0.80 | MAPK8 (0.46) | MAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL30844289 | 0.80 | CMA1 (0.44) | CALCRLMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773447-B | Application of ETGE polypeptide in preparation of medicines for treating multiple organ ischemia reperfusion injury | 华中科技大学同济医学院附属协和医院 | 2023-06-06 | — | — | CN | claimed |
| CN-114773447-B | Application of ETGE polypeptide in preparation of medicines for treating multiple organ ischemia reperfusion injury | 华中科技大学同济医学院附属协和医院 | 2023-06-06 | — | — | CN | disclosed |