Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | CALCRL | Q16602 | 6/20 | 0.45 |
| ▸ | REN | P00797 | 3/20 | 0.41 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582212 | 0.92 | MAPK8 (0.47) | MAPK8MAPK9MAPK10RENPTPN1 | |
| SCHEMBL29679831 | 0.90 | KDM1A (0.48) | MAPK8MAPK9MAPK10RENKDM1A | |
| SCHEMBL30019633 | 0.89 | KDM1A (0.45) | MAPK8MAPK9MAPK10RENKEAP1 | |
| SCHEMBL30416367 | 0.87 | CALCRL (0.46) | MAPK8MAPK9MAPK10CALCRLRAMP1 | |
| SCHEMBL29827418 | 0.87 | CALCRL (0.46) | MAPK8MAPK9MAPK10CALCRLRAMP1 | |
| SCHEMBL30199670 | 0.85 | MAPK8 (0.46) | MAPK8MAPK9MAPK10RENKEAP1 | |
| SCHEMBL30844289 | 0.85 | CMA1 (0.44) | MAPK8MAPK9MAPK10CALCRLREN | |
| SCHEMBL31259383 | 0.84 | REN (0.43) | MAPK8MAPK9MAPK10RENCMA1 | |
| SCHEMBL30997476 | 0.84 | MAPK8 (0.49) | MAPK8MAPK9MAPK10RENPTPN1 | |
| SCHEMBL30400982 | 0.84 | MAPK8 (0.48) | MAPK8MAPK9MAPK10CALCRLREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002461-A1 | FUSION PROTEIN FOR TREATING METABOLIC DISEASES, AND PREPARATION METHOD AND USE THEREOF | JIANGNAN UNIVERSITY (CN) | 2024-01-04 | — | — | US | claimed |
| US-11845781-B2 | Fusion protein comprising fibroblast growth factor 19 (FGF 19) and glucagon-like peptide-1 | JIANGNAN UNIVERSITY (CN) | 2023-12-19 | — | — | US | claimed |
| WO-2022257479-A1 | FUSION PROTEIN FOR TREATING METABOLIC DISEASES, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 江南大学 | 2022-12-15 | — | — | WO | claimed |
| WO-2022227707-A1 | PREPARATION METHOD FOR AND APPLICATION OF DOUBLE-TARGET FUSION PROTEIN | 江南大学 | 2022-11-03 | — | — | WO | claimed |
| US-12338271-B2 | Fusion protein including GIP and FGF21 and compositions thereof | JIANGNAN UNIVERSITY (CN) | 2025-06-24 | — | — | US | disclosed |
| US-20240002461-A1 | FUSION PROTEIN FOR TREATING METABOLIC DISEASES, AND PREPARATION METHOD AND USE THEREOF | JIANGNAN UNIVERSITY (CN) | 2024-01-04 | — | — | US | disclosed |
| US-11845781-B2 | Fusion protein comprising fibroblast growth factor 19 (FGF 19) and glucagon-like peptide-1 | JIANGNAN UNIVERSITY (CN) | 2023-12-19 | — | — | US | disclosed |
| US-20230265141-A1 | PREPARATION METHOD AND USE OF DOUBLE-TARGET FUSION PROTEIN | JIANGNAN UNIVERSITY (CN) | 2023-08-24 | — | — | US | disclosed |
| WO-2022257479-A1 | FUSION PROTEIN FOR TREATING METABOLIC DISEASES, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 江南大学 | 2022-12-15 | — | — | WO | disclosed |
| WO-2022227707-A1 | PREPARATION METHOD FOR AND APPLICATION OF DOUBLE-TARGET FUSION PROTEIN | 江南大学 | 2022-11-03 | — | — | WO | disclosed |