Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 4/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.43 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25384931 | 1.00 | ATM (0.43) | ATMCTSBCAPN1CAPN9MAPK1 | |
| SCHEMBL17870455 | 0.84 | CAPN1 (0.47) | CTSBCAPN1CAPN9MAPK1CTSL | |
| SCHEMBL17870456 | 0.84 | CAPN1 (0.47) | CTSBCAPN1CAPN9MAPK1CTSL | |
| SCHEMBL4236035 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1MAPTLMNAKMT2AHPGD | |
| SCHEMBL19137249 | 0.79 | HPGD (0.42) | ATMALDH1A1MAPTALPLLMNA | |
| SCHEMBL17870476 | 0.77 | CAPN1 (0.49) | CTSBCAPN1CAPN9MAPK1CTSL | |
| SCHEMBL6183239 | 0.76 | CTSL (0.66) | CTSBCTSLCTSSCTSK | |
| SCHEMBL18941372 | 0.76 | CAPN1 (0.62) | CTSBCAPN1CAPN9MAPK1CTSL | |
| SCHEMBL25330262 | 0.76 | CAPN1 (0.48) | CTSBCAPN1CAPN9MAPK1CTSL | |
| SCHEMBL7456823 | 0.76 | CTSL (0.66) | CTSBCTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4172188-A1 | CIS-BINDING SIGLEC AGONISTS AND RELATED COMPOSITIONS AND METHODS | The Board of Trustees of the Leland Stanford Junior University (US) | 2023-05-03 | — | — | EP | disclosed |