Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 18/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20068762 | 1.00 | DYRK1A (1.00) | DYRK1AALDH1A1CCNA2CDK2 | |
| SCHEMBL20068763 | 0.89 | DYRK1A (1.00) | DYRK1A | |
| SCHEMBL20068759 | 0.88 | DYRK1A (1.00) | DYRK1A | |
| SCHEMBL23015694 | 0.82 | DYRK1A (1.00) | DYRK1A | |
| SCHEMBL20068756 | 0.82 | DYRK1A (0.77) | DYRK1A | |
| SCHEMBL20068738 | 0.82 | DYRK1A (0.75) | DYRK1A | |
| SCHEMBL30833188 | 0.80 | DYRK1A (0.76) | DYRK1A | |
| SCHEMBL23015688 | 0.80 | DYRK1A (0.76) | DYRK1A | |
| SCHEMBL20069398 | 0.80 | DYRK1A (1.00) | DYRK1A | |
| SCHEMBL20068755 | 0.80 | DYRK1A (1.00) | DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843879-B | Benzothiazole derivatives as DYRK1 inhibitors | 药物治疗股份有限公司 | 2023-05-02 | — | — | CN | disclosed |