Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 20/20 | 0.76 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23015688 | 1.00 | DYRK1A (0.76) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL23015687 | 0.90 | DYRK1A (0.79) | DYRK1A | |
| SCHEMBL30833187 | 0.90 | DYRK1A (0.79) | DYRK1A | |
| SCHEMBL23015693 | 0.87 | DYRK1A (1.00) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL30417087 | 0.87 | DYRK1A (1.00) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL17553301 | 0.85 | DYRK1A (0.55) | DYRK1A | |
| SCHEMBL20068748 | 0.83 | DYRK1A (1.00) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| Hydrochloric Acid SCHEMBL29159571 | 0.82 | DYRK1A (0.98) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| Hydrochloric Acid SCHEMBL30417034 | 0.82 | DYRK1A (0.98) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL20068747 | 0.81 | DYRK1A (1.00) | DYRK1ACLK1CLK2DYRK2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526216-B1 | BENZOTHIAZOLE DERIVATIVES AS DYRK1 INHIBITORS | PHARMASUM THERAPEUTICS AS (NO) | 2024-04-03 | — | — | EP | disclosed |