Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22882716 | 0.91 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1HTTGFER | |
| SCHEMBL20362584 | 0.85 | PTGER1 (0.48) | ALDH1A1KMT2AMEN1HTTGFER | |
| SCHEMBL1838503 | 0.83 | ALDH1A1 (0.53) | ALDH1A1RXRAATMKMT2AMEN1 | |
| SCHEMBL1838436 | 0.82 | ALDH1A1 (0.51) | ALDH1A1ATMKMT2AMEN1HTT | |
| SCHEMBL24589174 | 0.81 | CA12 (0.51) | ALDH1A1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL6890110 | 0.81 | MAPT (0.51) | ALDH1A1KMT2AMEN1HTTPOLB | |
| SCHEMBL10582946 | 0.80 | KDM4E (0.60) | ALDH1A1KMT2AMEN1HTTGFER | |
| SCHEMBL9659120 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1KMT2AMEN1HTTGFER | |
| SCHEMBL9656962 | 0.80 | MEN1 (0.45) | ALDH1A1KMT2AMEN1HTTGFER | |
| SCHEMBL6947612 | 0.80 | MEN1 (0.70) | ALDH1A1KMT2AMEN1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111971277-B | Benzothiophenes and related compounds as STING agonists | 默沙东有限责任公司 | 2023-06-06 | — | — | CN | disclosed |