Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 19/20 | 0.63 |
| ▸ | KCNK9 | Q9NPC2 | 19/20 | 0.63 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19807667 | 0.89 | KDM4E (0.62) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL31020938 | 0.86 | KCNK3 (0.70) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL29432813 | 0.86 | KCNK3 (0.67) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL30417973 | 0.85 | KCNK3 (0.69) | KCNK3KCNK9 | |
| SCHEMBL29432833 | 0.83 | KDM4E (0.62) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL22269606 | 0.83 | KCNK3 (0.67) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL19807810 | 0.82 | KCNK3 (0.64) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL19807662 | 0.82 | KDM4E (0.65) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL19807871 | 0.81 | KCNK3 (0.77) | KCNK3KCNK9 | |
| Hydrochloric Acid SCHEMBL31448348 | 0.81 | KCNK3 (0.63) | KCNK3KCNK9SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452264-A1 | COMBINATION OF A TASK1/3 CHANNEL BLOCKER WITH A NOREPINEPHRINE REUPTAKE INHIBITOR FOR THE TREATMENT OF SLEEP APNEA | Bayer Aktiengesellschaft (DE) | 2024-10-30 | — | — | EP | disclosed |
| EP-4452263-A1 | COMBINATION OF A TASK1/3 CHANNEL BLOCKER WITH A P2X3 RECEPTOR ANTAGONIST FOR THE TREATMENT OF SLEEP APNEA | Bayer Aktiengesellschaft (DE) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023118126-A1 | COMBINATION OF A TASK1/3 CHANNEL BLOCKER WITH A NOREPINEPHRINE REUPTAKE INHIBITOR FOR THE TREATMENT OF SLEEP APNEA | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-29 | — | — | WO | disclosed |