Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 19/20 | 0.70 |
| ▸ | KCNK9 | Q9NPC2 | 19/20 | 0.70 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29458055 | 0.89 | KCNK3 (0.67) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL22269606 | 0.87 | KCNK3 (0.67) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL25249541 | 0.86 | KCNK3 (0.79) | KCNK3KCNK9 | |
| SCHEMBL30417275 | 0.86 | KCNK3 (0.63) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL21360488 | 0.86 | KCNK3 (0.67) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL19807762 | 0.82 | KCNK3 (0.62) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL21360483 | 0.82 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL21360470 | 0.82 | KCNK3 (1.00) | KCNK3KCNK9 | |
| Hydrochloric Acid SCHEMBL31448414 | 0.82 | KCNK3 (0.61) | KCNK3KCNK9SLC2A1 | |
| SCHEMBL19807810 | 0.82 | KCNK3 (0.64) | KCNK3KCNK9SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118785904-A | Conjugates of TASK1/3 channel blockers and P2X3 receptor antagonists for the treatment of sleep apnea | 拜耳公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118785904-A | Conjugates of TASK1/3 channel blockers and P2X3 receptor antagonists for the treatment of sleep apnea | 拜耳公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118541153-A | Conjugates of a TASK1/3 channel blocker and a norepinephrine reuptake inhibitor for the treatment of sleep apnea | 拜耳公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-118434415-A | Conjugates of TASK1/3 channel blockers and muscarinic receptor antagonists for the treatment of sleep apnea | 拜耳公司 | 2024-08-02 | — | — | CN | disclosed |