Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 1.00 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | PRKACG | P22612 | 1/20 | 0.43 |
| ▸ | PRKACB | P22694 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.43 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1945766 | 1.00 | PARP1 (1.00) | PARP1CCNE2CDK4PRKACAPRKACG | |
| SCHEMBL30090665 | 1.00 | PARP1 (1.00) | PARP1CCNE2CDK4PRKACAPRKACG | |
| SCHEMBL1946020 | 1.00 | PARP1 (1.00) | PARP1CCNE2CDK4PRKACAPRKACG | |
| SCHEMBL3443321 | 1.00 | PARP1 (1.00) | PARP1CCNE2CDK4PRKACAPRKACG | |
| Hydrochloric Acid SCHEMBL1946668 | 0.99 | PARP1 (0.98) | PARP1CCNE2CDK4PRKACAPRKACG | |
| Bromide SCHEMBL1944264 | 0.99 | PARP1 (0.98) | PARP1CCNE2CDK4PRKACAPRKACG | |
| Bromide SCHEMBL1944266 | 0.99 | PARP1 (0.98) | PARP1CCNE2CDK4PRKACAPRKACG | |
| Hydrochloric Acid SCHEMBL1946669 | 0.99 | PARP1 (0.98) | PARP1CCNE2CDK4PRKACAPRKACG | |
| Bromide SCHEMBL1946605 | 0.98 | PARP1 (0.96) | PARP1CCNE2CDK4PRKACAPRKACG | |
| Bromide SCHEMBL1946607 | 0.98 | PARP1 (0.96) | PARP1CCNE2CDK4PRKACAPRKACG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419094-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS | Edison Oncology (US) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023069727-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS | EDISON ONCOLOGY (US) | 2023-04-27 | — | — | WO | disclosed |