Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 10/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25290961 | 1.00 | ROCK2 (0.40) | ROCK2ROCK1CDC42BPBCHRNB2CHRNA4 | |
| SCHEMBL25293519 | 0.84 | PIM1 (0.45) | PIM2PIM3PIM1 | |
| SCHEMBL31145199 | 0.84 | PIM1 (0.45) | PIM2PIM3PIM1 | |
| SCHEMBL30417276 | 0.83 | PIM2 (0.42) | ROCK2ROCK1CDC42BPBCHRNB2CHRNA4 | |
| SCHEMBL25287892 | 0.83 | PIM2 (0.42) | ROCK2ROCK1CDC42BPBCHRNB2CHRNA4 | |
| SCHEMBL25286064 | 0.81 | PIM2 (0.42) | PIM2PIM3PIM1 | |
| SCHEMBL30417648 | 0.81 | PIM2 (0.42) | PIM2PIM3PIM1 | |
| SCHEMBL25244797 | 0.81 | PIM2 (0.42) | PIM2PIM3PIM1 | |
| SCHEMBL25246636 | 0.81 | PIM2 (0.42) | PIM2PIM3PIM1 | |
| SCHEMBL30417012 | 0.81 | PIM2 (0.42) | PIM2PIM3PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448769-A2 | APTAMERS AND SMALL MOLECULE LIGANDS | Meiragtx UK II Limited (GB) | 2024-10-23 | — | — | EP | disclosed |
| CN-118786217-A | Aptamer and small molecule ligand | 梅里特斯英国第二有限公司 | 2024-10-15 | — | — | CN | disclosed |
| WO-2023111686-A2 | APTAMERS AND SMALL MOLECULE LIGANDS | MEIRAGTX UK II LIMITED (GB) | 2023-06-22 | — | — | WO | disclosed |