Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 16/20 | 0.56 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2297910 | 1.00 | PARP1 (0.56) | PARP1GRM2DHODHPARP2CHEK2 | |
| SCHEMBL2299794 | 0.91 | PARP1 (0.56) | PARP1GRM2DHODHPARP2CHEK2 | |
| SCHEMBL2294120 | 0.89 | PARP1 (0.57) | PARP1DHODHPARP2CHEK2 | |
| SCHEMBL2294128 | 0.89 | PARP1 (0.57) | PARP1DHODHPARP2CHEK2 | |
| SCHEMBL30418282 | 0.89 | PARP1 (0.57) | PARP1DHODHPARP2CHEK2 | |
| SCHEMBL30418224 | 0.89 | PARP1 (0.57) | PARP1DHODHPARP2CHEK2 | |
| SCHEMBL2295375 | 0.89 | PARP1 (0.57) | PARP1DHODHPARP2CHEK2 | |
| SCHEMBL2296230 | 0.88 | PARP1 (0.67) | PARP1DHODHPARP2 | |
| SCHEMBL2299796 | 0.88 | PARP1 (0.58) | PARP1DHODHPARP2 | |
| SCHEMBL2298595 | 0.87 | PARP1 (0.57) | PARP1DHODHPARP2CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419094-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS | Edison Oncology (US) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023069727-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS | EDISON ONCOLOGY (US) | 2023-04-27 | — | — | WO | disclosed |