SCHEMBL30419451

SCHEMBL30419451

NCCCC[C@H](NC(=O)CN)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.43
GSTK1 Q9Y2Q3 1/20 0.43
SIRT6 Q8N6T7 1/20 0.43
SIRT1 Q96EB6 1/20 0.43
NMT1 P30419 5/20 0.43
NMT2 O60551 4/20 0.43
FOLH1 Q04609 1/20 0.42
SLC15A2 Q16348 1/20 0.42
GLO1 Q04760 1/20 0.41
SLC6A5 Q9Y345 1/20 0.40
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38
TERT O14746 1/20 0.38
F2 P00734 1/20 0.37
RNPEP Q9H4A4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29714945 1.00 PTGS1 (0.43) PTGS1GSTK1SIRT6SIRT1NMT1
SCHEMBL29801954 1.00 PTGS1 (0.43) PTGS1GSTK1SIRT6SIRT1NMT1
SCHEMBL30843077 0.96 PTGS1 (0.42) PTGS1GSTK1SIRT6SIRT1NMT1
SCHEMBL30026553 0.96 PTGS1 (0.42) PTGS1GSTK1SIRT6SIRT1NMT1
SCHEMBL30102096 0.96 PTGS1 (0.42) PTGS1GSTK1SIRT6SIRT1NMT1
SCHEMBL30561241 0.96 PTGS1 (0.42) PTGS1GSTK1SIRT6SIRT1NMT1
SCHEMBL29427845 0.96 PTGS1 (0.42) PTGS1GSTK1SIRT6SIRT1NMT1
SCHEMBL29714931 0.96 PTGS1 (0.42) PTGS1GSTK1SIRT6SIRT1NMT1
SCHEMBL4188063 0.96 PTGS1 (0.46) PTGS1GSTK1SIRT6SIRT1NMT1
SCHEMBL27739976 0.96 PTGS1 (0.46) PTGS1GSTK1SIRT6SIRT1NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4429710-A1 METHOD FOR PRODUCING AN ANTIBODY PEPTIDE CONJUGATE Amgen Inc. (US) 2024-09-18 EP disclosed
WO-2023086790-A1 METHOD FOR PRODUCING AN ANTIBODY PEPTIDE CONJUGATE AMGEN INC. (US) 2023-05-19 WO disclosed