SCHEMBL4188063

SCHEMBL4188063

NCCCC[C@H](NC(=O)CN)C(=O)NCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.46
GSTK1 Q9Y2Q3 1/20 0.46
SIRT6 Q8N6T7 1/20 0.46
SIRT1 Q96EB6 1/20 0.46
FOLH1 Q04609 1/20 0.45
NMT1 P30419 5/20 0.45
NMT2 O60551 4/20 0.45
SLC15A2 Q16348 1/20 0.44
GLO1 Q04760 1/20 0.43
SLC6A5 Q9Y345 1/20 0.42
ITGB3 P05106 1/20 0.40
ITGA2B P08514 1/20 0.40
RNPEP Q9H4A4 1/20 0.40
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27739976 1.00 PTGS1 (0.46) PTGS1GSTK1SIRT6SIRT1FOLH1
SCHEMBL27739982 1.00 PTGS1 (0.46) PTGS1GSTK1SIRT6SIRT1FOLH1
SCHEMBL29801954 0.96 PTGS1 (0.43) PTGS1GSTK1SIRT6SIRT1FOLH1
SCHEMBL30419451 0.96 PTGS1 (0.43) PTGS1GSTK1SIRT6SIRT1FOLH1
SCHEMBL29714945 0.96 PTGS1 (0.43) PTGS1GSTK1SIRT6SIRT1FOLH1
SCHEMBL29801851 0.93 PTGS1 (0.43) PTGS1GSTK1SIRT6SIRT1FOLH1
SCHEMBL29373405 0.92 FOLH1 (0.52) PTGS1GSTK1SIRT6SIRT1FOLH1
SCHEMBL30026553 0.91 PTGS1 (0.42) PTGS1GSTK1SIRT6SIRT1FOLH1
SCHEMBL29714931 0.91 PTGS1 (0.42) PTGS1GSTK1SIRT6SIRT1FOLH1
SCHEMBL29427845 0.91 PTGS1 (0.42) PTGS1GSTK1SIRT6SIRT1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4684807-A1 LINKER AND USE THEREOF IN LIGAND DRUG CONJUGATE Duality Biologics (Shanghai) Co., Ltd. (CN) 2026-01-28 EP claimed
CN-119300868-A Camptothecins compound and conjugate thereof, preparation method and application thereof 映恩生物科技(上海)有限公司 2025-01-10 CN claimed
CN-119053607-A Camptothecins compound and conjugate thereof, preparation method and application thereof 映恩生物科技(上海)有限公司 2024-11-29 CN claimed
WO-2024193692-A1 LINKER AND USE THEREOF IN LIGAND DRUG CONJUGATE 映恩生物制药(苏州)有限公司 2024-09-26 WO claimed
CN-118684724-A Linker and use thereof in ligand drug conjugates 映恩生物制药(苏州)有限公司 2024-09-24 CN claimed
CN-122080121-A Linker and use thereof in ligand drug conjugates 2026-05-26 CN disclosed
EP-4710946-A1 MULTI-PROJECTILE ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Medilink Therapeutics (Suzhou) Co., Ltd. (CN) 2026-03-18 EP disclosed
EP-4684807-A1 LINKER AND USE THEREOF IN LIGAND DRUG CONJUGATE Duality Biologics (Shanghai) Co., Ltd. (CN) 2026-01-28 EP disclosed
EP-4544047-A2 ENGINEERED TRNA AND METHODS OF USE The University of Chicago (US) 2025-04-30 EP disclosed
CN-119731319-A Engineered tRNA and methods of use thereof 芝加哥大学 2025-03-28 CN disclosed
CN-119300868-A Camptothecins compound and conjugate thereof, preparation method and application thereof 映恩生物科技(上海)有限公司 2025-01-10 CN disclosed
CN-119053607-A Camptothecins compound and conjugate thereof, preparation method and application thereof 映恩生物科技(上海)有限公司 2024-11-29 CN disclosed
WO-2023250446-A2 ENGINEERED tRNA AND METHODS OF USE THE UNIVERSITY OF CHICAGO (US) 2023-12-28 WO disclosed
US-20230109312-A1 NOVEL LINKERS FOR ANTIBODY-DRUG CONJUGATES AND RELATED COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IGENICA BIOTHERAPEUTICS, INC. 2023-04-06 US disclosed
CN-115279905-A Synthetic RIG-I like receptor agonists 里珍纳龙药品有限公司 2022-11-01 CN disclosed
US-20220267379-A1 NOVEL INHIBITORS OF KALLIKREIN PROTEASES AND USES THEREOF UNIVERSITÉ PARIS CITÉ (FR) 2022-08-25 US disclosed
EP-3999530-A1 NOVEL INHIBITORS OF KALLIKREIN PROTEASES AND USES THEREOF ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2022-05-25 EP disclosed
US-11229711-B2 Linkers for antibody-drug conjugates and related compounds, compositions, and methods of use Magenta Therapeutics, Inc. (US) 2022-01-25 US disclosed
US-20090215986-A1 Solution Synthesis of Peptide Cell Growth Stimulators EPSTEIN DAVID 2009-08-27 US disclosed
US-20070213505-A1 Solution Synthesis of Peptide Cell Growth Stimulators EPSTEIN DAVID 2007-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230109312-A1 NOVEL LINKERS FOR ANTIBODY-DRUG CONJUGATES AND RELATED COMPOUNDS, COMPOSITIONS, AND METHODS OF USE SDCBP, DCLRE1A, BCR PTGS1 3783/4885GSTK1 1255/4885SIRT6 2321/4885
US-11229711-B2 Linkers for antibody-drug conjugates and related compounds, compositions, and methods of use CLSPN, SDCBP, DCLRE1A PTGS1 4086/4885GSTK1 1922/4885SIRT6 1932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.