Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.91 |
| ▸ | NPC1 | O15118 | 3/20 | 0.78 |
| ▸ | RAB9A | P51151 | 3/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | LTA4H | P09960 | 1/20 | 0.70 |
| ▸ | ACHE | P22303 | 1/20 | 0.70 |
| ▸ | RAD52 | P43351 | 1/20 | 0.70 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027800 | 0.98 | TSHR (0.88) | TSHRNPC1RAB9ATP53HPGD | |
| SCHEMBL3037458 | 0.95 | TSHR (0.82) | TSHRNPC1RAB9ATP53HPGD | |
| SCHEMBL1044760 | 0.92 | RAB9A (0.91) | TSHRNPC1RAB9ATP53HPGD | |
| SCHEMBL1046370 | 0.87 | TSHR (0.84) | TSHRNPC1RAB9ATP53HPGD | |
| SCHEMBL24514228 | 0.87 | RAB9A (1.00) | TSHRNPC1RAB9ATP53HPGD | |
| SCHEMBL27640984 | 0.85 | HRH3 (0.70) | TSHRHRH3ACHERAD52 | |
| SCHEMBL28760646 | 0.85 | HRH3 (0.70) | TSHRHRH3ACHERAD52 | |
| SCHEMBL27661481 | 0.85 | HRH3 (0.70) | TSHRHRH3ACHERAD52 | |
| SCHEMBL27661480 | 0.85 | HRH3 (0.70) | TSHRHRH3ACHERAD52 | |
| SCHEMBL3571025 | 0.84 | HRH3 (0.79) | TSHRHRH3ACHERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | ABBOTT LABORATORIES (US) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | S1PR5, LPAR5, S1PR1 | TSHR 1839/4885NPC1 965/4885RAB9A 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.