Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 4/20 | 0.44 |
| ▸ | FNTB | P49356 | 4/20 | 0.44 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.42 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.40 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | CALCR | P30988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30420753 | 0.93 | GRB2 (0.47) | GRB2NAA50APLNRCXCL8KEAP1 | |
| SCHEMBL30420502 | 0.93 | GRB2 (0.49) | GRB2NAA50NMUR2NMUR1CXCL8 | |
| SCHEMBL30420364 | 0.92 | NAA50 (0.49) | GRB2FNTAFNTBNAA50APLNR | |
| SCHEMBL31232442 | 0.89 | GRB2 (0.51) | GRB2NAA50APLNRNTSR1NTSR2 | |
| SCHEMBL30419465 | 0.87 | NAA50 (0.53) | GRB2NAA50NMUR2NMUR1CXCL8 | |
| SCHEMBL30420836 | 0.86 | NAA50 (0.50) | GRB2NAA50KEAP1NTSR1CALCR | |
| SCHEMBL30987363 | 0.85 | NMUR2 (0.41) | GRB2NMUR2CXCL8NTSR1NTSR2 | |
| SCHEMBL30853505 | 0.85 | GRB2 (0.55) | GRB2NMUR2NMUR1NTSR1NTSR2 | |
| SCHEMBL29462926 | 0.85 | GRB2 (0.54) | GRB2NAA50APLNRNTSR1NTSR2 | |
| SCHEMBL31332114 | 0.84 | CALCRL (0.48) | GRB2FNTAFNTBCXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116350760-A | Application of CTL epitope peptide derived from new antigen ESR1 or encoding nucleic acid thereof in preparation of medicines | 郑州大学 | 2023-06-30 | — | — | CN | disclosed |