SCHEMBL30420577

SCHEMBL30420577

N=C(N)NCCC[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 11/20 0.64
NPY1R P25929 6/20 0.64
NPY2R P49146 4/20 0.64
NPY5R Q15761 4/20 0.64
MMP2 P08253 1/20 0.53
OPRM1 P35372 1/20 0.51
CTSL P07711 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29461999 1.00 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL31694494 0.99 NPY4R (0.66) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL29641039 0.97 NPY4R (0.68) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL29641110 0.97 NPY4R (0.68) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL29641042 0.95 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL22133073 0.95 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL29641040 0.95 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL29641130 0.95 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL29641095 0.95 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL8975469 0.94 NPY4R (0.73) NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4422645-A2 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF Wave Life Sciences Ltd. (SG) 2024-09-04 EP disclosed
US-20230293624-A1 METHODS FOR PREVENTING OR TREATING MITOCHONDRIAL PERMEABILITY TRANSITION CORNELL RESEARCH FOUNDATION, INC. (US) 2023-09-21 US disclosed
WO-2023076352-A2 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-05-04 WO disclosed
WO-2023075766-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-05-04 WO disclosed